DCAMKL1, active

Background Information:

DCAMKL1 is a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. GenBank NM_004734.2

Target Class:

Kinase

Family:

CAMK

Sub Family:

Protein Ser/Thr

Protein Name:

DCAMKL1

Protein Aliases:

Doublecortin domain-containing protein 3A|Doublecortin-like and CAM kinase-like 1|Doublecortin-like kinase 1

Accession Number:

NM_004734.2

UniProt Number:

O15075

Gene Name:

DCLK1

Gene ID:

9201

Gene Aliases:

KIAA0369|DCLK|DCDC3A

Target Species:

Human