Biological Information

Background Information:

IRR protein is a receptor with tyrosine-protein kinase activity. It functions as a pH sensing receptor which is activated by increased extracellular pH. It activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB. GenBank NM_014215

Target Class:

Kinase

Family:

RTK

Sub Family:

Protein Tyrosine

Protein Name:

IRR

Protein Aliases:

IR-related receptor [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]

Accession Number:

NM_014215.1

UniProt Number:

P14616

Gene Name:

INSRR

Gene ID:

3645

Gene Aliases:

IRR

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Bioassay Data

Trademark Statement:

For Research Use Only

Clinical Relevance

Therapeutic Area:

Metabolic Diseases