Biological Information

Background Information:

Recombinant human MELK (amino acids 1 - 340), containing an N-terminal GST tag. Maternal embryonic leucine zipper kinase (MELK) is a conserved serine/threonine kinase involved in a variety of cellular functions, including proliferation, differentiation and apoptosis. Its levels are elevated in a number of tumor types and it may be a prognosis marker for some cancers.

Target Class:

Kinase

Family:

CAMK

Sub Family:

Protein Ser/Thr

Protein Name:

MELK

Protein Aliases:

Protein kinase Eg3|pEg3 kinase|Protein kinase PK38|hPK38|Tyrosine-protein kinase MELK

Accession Number:

NM_014791.2

UniProt Number:

Q14680

Gene Name:

MELK

Gene ID:

9833

Gene Aliases:

KIAA0175

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

6 months at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology