Biological Information

Background Information:

VRK2 is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This protein is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, leukocytes, fetal liver, and carcinomas. Its protein localizes to the endoplasmic reticulum and has been shown to phosphorylate casein and undergo autophosphorylation. Multiple alternatively spliced transcript variants have been found for this gene.

Target Class:

Kinase

Family:

CK1

Sub Family:

Protein Ser/Thr

Protein Name:

VRK2

Protein Aliases:

Vaccinia-related kinase 2

Accession Number:

NM_006296

UniProt Number:

Q86Y07

Gene Name:

VRK2

Gene ID:

7444

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Bioassay Data

Trademark Statement:

For Research Use Only