Biological Information

Background Information:

The ChemiSCREEN™ MC1 Melanocortin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of MC1R surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.

Target Class:

GPCR

Family:

Melanocortin

Sub Family:

Class A

Protein Name:

MC1

Protein Aliases:

alpha melanocyte stimulating hormone receptor

Accession Number:

NM_002386

UniProt Number:

Q01726

Gene Name:

MC1R

Gene ID:

4157

Gene Aliases:

MSH-R|MSHR

Target Species:

Human

Cell Background:

Chem-1

Usage

Product Type:

Membrane Preparations

Application:

Drug Discovery & Development

Storage Conditions:

Vial to be stored at -70°C. Avoid repeat freeze/thaw cycles.

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Cell Based

Assay Measures:

Binding & GTPγS Function

Detection Method:

Fluorescence, Radioactivity

Additional Information

Brand:

ChemiSCREEN™