ChemiSCREEN™ V2 Vasopressin Receptor Membrane Preparation

Background Information:

The ChemiSCREEN™ V2 Vasopressin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of AVPR2 surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.

Target Class:

GPCR

Family:

Vasopressin and Oxytocin

Sub Family:

Class A

Protein Name:

V2

Protein Aliases:

nephrogenic diabetes insipidus

Accession Number:

NM_000054.4; NM_001146151

UniProt Number:

P30518

Gene Name:

AVPR2

Gene ID:

554

Gene Aliases:

ADHR|DIR|DIR3|V2R

Target Species:

Human

Cell Background:

Chem-1