Biological Information

Background Information:

N-terminal 6His-tagged recombinant, human Met amino acids 974-end, containing the mutation Y1248D. Met Y1248D is a germline mutation that has been identified in patients with hereditary papillary renal carcinomas (HPRC). in vitro studies have demonstrated that this mutation has a moderate transforming ability.

Target Class:

Kinase

Family:

RTK

Sub Family:

Protein Tyrosine

Protein Name:

Met

Protein Aliases:

hepatocyte growth factor receptor

Accession Number:

NM_000245.2

UniProt Number:

P08581

Gene Name:

MET

Gene ID:

4233

Gene Aliases:

HGFR|RCCP2|DFNB97

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

6 months at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology