Biological Information
Background Information:
NEK4 is a serine/threonine protein kinase required for normal entry into replicative senescence. The encoded protein also is involved in cell cycle arrest in response to double-stranded DNA damage. Finally, this protein plays a role in maintaining cilium integrity, and defects in this gene have been associated with ciliopathies. [provided by RefSeq, Jan 2017]
Target Class:
Kinase
Family:
Other Protein Kinase
Sub Family:
Protein Ser/Thr
Protein Name:
NEK4
Protein Aliases:
serine/threonine protein kinase-2
Accession Number:
NM_003157.4
UniProt Number:
P51957
Gene Name:
NEK4
Gene ID:
6787
Gene Aliases:
NRK2|pp12301
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
Usage disclaimer:
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Assay Information
Assay Type:
Enzymatic
Bioassay Data
Trademark Statement:
For Research Only
Clinical Relevance
Therapeutic Area:
Oncology/Immuno-Oncology