PTPMEG-1

Background Information:

PTPMEG-1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in Signaling downstream of the glutamate receptors through tyrosine dephosphorylation. GenBank NM_002830

Target Class:

Phosphatase

Family:

Non-Receptor

Sub Family:

Protein Tyrosine

Protein Name:

PTPMEG

Accession Number:

NM_002830.2

UniProt Number:

P29074

Gene Name:

PTPN4

Gene ID:

5775

Gene Aliases:

PTPMEG

Target Species:

Human